Methylphenidate and its Enantiomers
نویسندگان
چکیده
منابع مشابه
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1.
Methylphenidate is an important stimulant prescribed to treat attention-deficit hyperactivity disorder. It has two chiral centers, but most current commercial formulations consist of the racemic mixture of the threo pair of methylphenidate isomers (d-, l-threo-methylphenidate). The d-isomer is the pharmacologically active component. Numerous studies reported that oral administration of the meth...
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تاریخ انتشار 2003